Uncapped players Ryan Rickelton and Otniel Bartman have also been selected in the squad.
Kagiso Rabada and Nortje lead the pace attack, supported by Marco Jensen and Gerald Coetzee, while Bjorn Fortuyn, Keshav Maharaj and Tabraiz Shamsi lead the spin department.
South Africa team:
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Aiden Markram (captain), Ottneil Bartman, Gerald Coetzee, Quinton de Kock, Bjorn Fortuyn, Reeza Hendricks, Marco Jansen, Heinrich Klaasen, Keshav Maharaj, David Miller, Anrich Nortje, Kagiso Rabada, Ryan Rickelton, Tabraiz Shamsi, Tristan Stubbs.
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Travel Reserve: Nandre Burger and Lungi Ngidi